How long does a tick tablet act for dogs? - briefly
Oral tick preventatives typically protect dogs for about one month after administration, though certain formulations extend coverage to 8–12 weeks. The duration depends on the active ingredient and the specific product label.
How long does a tick tablet act for dogs? - in detail
Tick tablets for canines are designed to provide systemic protection against ticks for a defined period after administration. The duration of efficacy typically ranges from 30 to 90 days, depending on the active ingredient, dosage, and the dog’s physiological characteristics.
The most common active compounds and their reported protection windows are:
- Afoxolaner (NexGard, Bravecto® Chew) – 30 days of continuous tick kill.
- Fluralaner (Bravecto® Chew) – up to 12 weeks (approximately 84 days) of activity.
- Sarolaner (Simparica®, Simparica Trio®) – 30 days of protection.
- Lotilaner (Credelio®) – 30 days of efficacy.
Factors that influence how long a tablet remains effective:
- Body weight and dosage – Under‑dosing reduces plasma concentration, shortening the protective window; overdosing does not extend it beyond the labeled period.
- Metabolic rate – Younger, more active dogs may clear the drug faster, potentially reducing efficacy duration.
- Health status – Liver or kidney impairment can alter drug clearance, sometimes extending or diminishing the effective period.
- Formulation stability – Some products contain extended‑release matrices that sustain blood levels longer than others.
- Tick species – Certain ticks require higher drug concentrations for kill; efficacy may appear shorter against resistant species.
Pharmacokinetic considerations:
- After oral ingestion, the tablet is absorbed through the gastrointestinal tract, reaching peak plasma levels within 2–4 hours.
- The drug binds to plasma proteins, circulating systemically and being ingested by feeding ticks.
- Elimination half‑life varies: afoxolaner ≈ 12 days, fluralaner ≈ 12 weeks, sarolaner ≈ 9 days, lotilaner ≈ 4 weeks. The half‑life directly determines the length of protection.
Practical guidance:
- Administer the tablet on schedule recommended by the manufacturer (monthly or every 12 weeks) to maintain uninterrupted coverage.
- Verify the dog’s weight category before purchase; an incorrect dose compromises the intended protection period.
- Monitor for adverse reactions; if severe, discontinue and consult a veterinarian, as continued dosing will not improve efficacy but may increase risk.
In summary, systemic tick tablets provide protection ranging from one month to three months, with the exact timeframe dictated by the specific active ingredient, dosage accuracy, and individual dog factors. Consistent, correctly timed dosing is essential to sustain the intended protective period.