How to make a medicine for lice? - briefly
Combine a 1% permethrin solution with a gentle shampoo base, apply thoroughly to the scalp, leave for ten minutes, then rinse; repeat the treatment in one week to eliminate any newly hatched insects. Use a fine-toothed comb to remove dead nits after each application.
How to make a medicine for lice? - in detail
Lice infestations require a topical formulation that kills the parasite while minimizing irritation to the scalp. The following protocol outlines a complete, laboratory‑grade preparation for a lice‑killing solution.
Ingredients
- 1 % permethrin (pure active ingredient)
- 5 % dimethyl sulfoxide (penetration enhancer)
- 94 % distilled water, pH‑adjusted to 7.0 with sodium hydroxide solution
- Optional: 0.5 % piperonyl butoxide (synergist)
All components must meet pharmaceutical‑grade specifications. Use a calibrated balance for accurate measurement.
Preparation steps
- Place a clean, glass beaker on a magnetic stirrer.
- Add the distilled water and begin stirring at 300 rpm.
- Slowly introduce dimethyl sulfoxide while maintaining temperature below 25 °C.
- Dissolve permethrin by adding it dropwise; continue stirring until the mixture becomes clear.
- If a synergist is used, incorporate it after the permethrin has fully dissolved.
- Verify pH; adjust with dilute sodium hydroxide if necessary.
- Filter the solution through a 0.22 µm membrane filter into a sterile amber bottle.
Application protocol
- Apply a generous amount to dry hair, ensuring thorough coverage of the scalp and hair shafts.
- Massage gently for 30 seconds to promote contact.
- Leave the preparation on for 10 minutes, then rinse with lukewarm water.
- Repeat the procedure after 7 days to eliminate newly hatched nymphs.
Safety measures
- Wear nitrile gloves and eye protection during preparation.
- Conduct a patch test on a small skin area before full application; discontinue use if erythema or burning occurs.
- Keep the product out of reach of children and pets.
Storage and disposal
- Store the bottle in a cool, dark place at 4–8 °C.
- Label with concentration, preparation date, and expiration (12 months).
- Dispose of waste according to local hazardous‑chemical regulations; do not pour residual solution down the drain.
Following this detailed method yields a consistent, effective lice treatment suitable for clinical or home use under professional supervision.