How long does Frontline work against ticks? - briefly
Frontline protects dogs and cats from ticks for roughly 30 days after a single application. Efficacy stays high throughout that month, after which re‑treatment is needed.
How long does Frontline work against ticks? - in detail
Frontline is a topical ectoparasiticide that combines fipronil with (S)-methoprene to eliminate and repel ticks on dogs and cats. The formulation spreads across the skin surface, where fipronil interferes with the nervous system of the parasite, and (S)-methoprene prevents development of immature stages.
A single dose provides protection for up to 30 days against the most common tick species (e.g., brown dog tick, American dog tick, deer tick, and lone‑star tick). Laboratory and field trials demonstrate >90 % mortality within 24–48 hours after attachment, and the product maintains lethal concentrations throughout the month.
Key variables that can shorten or extend the protection period include:
- Correct dosage based on animal weight; under‑dosing reduces residual levels.
- Application site; the product must reach the skin, not just the coat.
- Bathing, swimming, or heavy rain within 24 hours of treatment, which can wash away a portion of the active ingredients.
- High ambient temperatures that increase skin metabolism and may accelerate degradation.
- Heavy tick pressure or infestations with resistant strains, which may require more frequent applications.
For optimal results, apply the product at the base of the neck, ensure the skin is clean and dry, and repeat the treatment every four weeks regardless of visible tick activity. This schedule sustains the lethal concentration on the animal’s skin, preventing re‑infestation and limiting disease transmission.