How long does Bravecto for dogs take to work as a tick tablet? - briefly
Bravecto begins killing attached ticks within 12 hours, with the majority eliminated by 24 hours after a single oral dose. Full protective effect against new infestations is established within 48 hours.
How long does Bravecto for dogs take to work as a tick tablet? - in detail
Bravecto chewable tablets contain the active ingredient fluralaner, a systemic ectoparasiticide absorbed from the gastrointestinal tract. After ingestion, peak plasma concentrations are typically reached within 3–5 hours. Therapeutic levels sufficient to kill attached ticks are established shortly after this peak.
Ticks that attach within the first 12 hours post‑administration are generally eliminated within 24 hours. Efficacy studies demonstrate that 95 % of Ixodes ricinus and Rhipicephalus sanguineus are killed by the end of the first day, with complete eradication observed by 48 hours. Protective effect against new infestations persists for up to 12 weeks, during which newly attached ticks are killed within 24–48 hours of attachment.
Factors that may modify the onset of action include:
- Body weight: dosage is calibrated per kilogram; under‑dosing can delay effective plasma levels.
- Food intake: administration with a meal enhances absorption, potentially shortening the time to peak concentration.
- Health status: hepatic or renal impairment may affect drug metabolism, marginally extending the period before therapeutic levels are achieved.
For optimal protection, administer the tablet at least 24 hours before anticipated exposure to tick‑infested environments. Observe the dog for signs of tick attachment during the first two days; any surviving ticks should be removed promptly, as they may have fed before systemic action fully engaged.
In summary, systemic activity commences within a few hours, with most ticks killed by the end of the first day and full protective coverage maintained for three months.