How is Unidox Solutab used after a tick bite?

How is Unidox Solutab used after a tick bite? - briefly

The tablet is dissolved in a specified volume of water and the resulting solution is taken orally as soon as possible after removal of the tick, typically a single dose of 500 mg of «Unidox Solutab». A second identical dose is administered 12 hours later to complete prophylactic coverage.

How is Unidox Solutab used after a tick bite? - in detail

Unidox Solutab is a reconstituted oral doxycycline formulation indicated for prophylactic treatment after a tick bite that carries a risk of Lyme disease. The regimen begins as soon as possible, preferably within 72 hours of exposure, and follows a precise schedule.

The recommended protocol includes:

  • Reconstitution of one 100 mg vial with 5 mL of water, producing a suspension of 20 mg/mL.
  • Ingestion of a single 200 mg dose (10 mL of the suspension) orally, without regard to meals.
  • Continuation of the same dose once daily for a total of three consecutive days.
  • Completion of the course even if the bite site appears normal and no symptoms have manifested.

Key considerations:

  • Verify that the patient has no known hypersensitivity to tetracyclines, no severe liver or renal impairment, and is not pregnant or lactating.
  • Record the exact time of the bite, species of tick (if identifiable), and any concurrent medications to assess potential drug interactions.
  • Advise monitoring for common adverse effects such as gastrointestinal upset, photosensitivity, or mild hepatic enzyme elevation; discontinue if severe reactions occur.
  • Document the outcome, noting any emergence of erythema migrans or systemic symptoms, and adjust management accordingly.

The effectiveness of this prophylaxis relies on prompt administration, adherence to the three‑day dosing schedule, and appropriate patient selection.