How do Barss drops for cats work on fleas? - briefly
Barss drops contain an insecticide that interferes with the flea nervous system, killing parasites on contact and halting their life cycle. The solution is absorbed through the cat’s skin and distributes systemically, providing protection for several weeks.
How do Barss drops for cats work on fleas? - in detail
Barss feline flea drops contain a synthetic insecticide blended with a rapid‑acting neurotoxin. After topical application, the solution spreads across the cat’s skin through natural oil distribution, reaching the epidermis and hair follicles within minutes. The active molecule penetrates the exoskeleton of attached fleas, binding to voltage‑gated chloride channels in their nervous system. This interaction forces continuous opening of the channels, causing uncontrolled influx of chloride ions, hyperpolarization of nerve cells, paralysis, and death within 30‑60 minutes.
The formulation also includes an insect growth regulator (IGR) that interferes with flea development. By mimicking juvenile hormone, the IGR prevents eggs and larvae from maturing into viable adults. As a result, the product reduces both adult flea populations and future generations for up to four weeks.
Key pharmacokinetic steps:
- Absorption: Lipophilic carrier enables swift permeation through the stratum corneum.
- Distribution: Systemic spread is limited; the majority of the dose remains on the skin surface, minimizing internal exposure.
- Metabolism: Enzymatic breakdown in the skin generates inactive metabolites, which are excreted via grooming or shedding.
- Elimination: Residual product is removed through normal grooming behavior, with negligible environmental contamination.
Safety considerations:
- Designed for cats weighing at least 2 kg; dosage is calibrated to body weight.
- Contra‑indicated for cats with known hypersensitivity to the active ingredients.
- Avoid contact with eyes, mucous membranes, and open wounds.
- Do not apply to pregnant or lactating queens without veterinary approval.
Resistance management:
- The dual‑action mechanism (neurotoxic kill plus growth inhibition) lowers the likelihood of resistance development.
- Rotating with products that use alternative classes of actives can further delay resistance.
Application protocol:
- Part the cat’s fur at the base of the skull.
- Apply the measured dose directly onto the skin, avoiding the hair shaft.
- Allow the cat to remain undisturbed for at least five minutes to ensure absorption.
- Repeat the treatment every four weeks or as directed by a veterinarian.
By delivering a rapid adulticide effect together with a long‑acting developmental inhibitor, Barss drops provide comprehensive flea control for domestic cats.