How to apply aversectin ointment for ear mites in cats?

Understanding Ear Mites in Cats

What Are Ear Mites?

Ear mites are microscopic parasites of the family Demodex that inhabit the external ear canal of cats. They feed on skin debris and secretions, causing irritation, inflammation, and a characteristic dark, crumbly discharge. Infestation spreads easily through direct contact with an affected animal or contaminated bedding, making rapid identification crucial for preventing colony-wide outbreaks.

Typical signs include frequent head shaking, scratching at the ears, and a foul odor. The ear canal often appears reddened and swollen, and a microscopic examination of the discharge reveals the translucent, oval-shaped mites. Laboratory confirmation allows targeted therapy and avoids unnecessary medication.

Effective treatment hinges on eliminating the mites and reducing inflammation. A topical antiparasitic ointment containing aversectin delivers a concentrated dose directly to the affected area, ensuring the active ingredient contacts the parasites within the canal. Application guidelines recommend:

Clean the ear gently with a veterinarian‑approved solution to remove debris.
Administer the prescribed amount of ointment into the ear canal, following the dosage chart based on the cat’s weight.
Massage the base of the ear for 30 seconds to distribute the medication evenly.
Repeat the procedure according to the product’s schedule, usually once daily for several days, to break the mite life cycle.

Monitoring the cat’s ears after treatment helps confirm eradication; persistent symptoms may indicate resistance or secondary infection and warrant veterinary reassessment.

Symptoms of Ear Mites

Ear mites (Otodectes cynotis) produce a distinct set of clinical signs in cats. The most common manifestations are:

Intense pruritus localized to the ear canal, prompting frequent scratching or rubbing of the head against objects.
Repetitive head shaking or tilting, often accompanied by a characteristic “dog‑ear” posture.
Accumulation of dark, crumbly debris resembling coffee grounds within the ear canal.
Redness and swelling of the ear canal walls, sometimes extending to the outer ear margin.
Secondary bacterial or yeast infection, indicated by a foul odor, increased discharge, or ulceration.
Behavioral changes such as irritability or reduced appetite due to discomfort.

Recognition of these symptoms enables prompt treatment with appropriate otic medication, such as aversectin ointment, to eliminate the infestation and prevent complications.

When to Suspect Ear Mites

Ear mites (Otodectes cynotis) are a common cause of feline ear problems. Recognizing the infestation early prevents discomfort and secondary infections, allowing timely use of aversectin ointment for treatment.

Typical indicators that a cat may harbor ear mites include:

Frequent head shaking or tilting.
Persistent scratching of the ears or surrounding area.
Dark, crumbly debris resembling coffee grounds in the ear canal.
Noticeable foul odor emanating from the ears.
Redness, swelling, or ulceration of the ear canal lining.
Decreased responsiveness to sounds or apparent hearing loss.
Recurring ear infections despite standard care.

Cats most vulnerable to infestation are kittens, indoor‑outdoor animals, and those living in multi‑cat environments where close contact facilitates mite transmission. If any combination of the above signs appears, a veterinary examination is warranted to confirm the diagnosis and initiate appropriate topical therapy.

Preparing for Aversectin Application

Consulting Your Veterinarian

When ear mite treatment involves a specialized ointment, professional guidance is indispensable. A veterinarian can confirm the diagnosis, rule out concurrent ear infections, and verify that aversectin is the appropriate medication for the specific cat.

The clinician will provide precise instructions on dosage, application frequency, and duration. They will also explain how to prepare the cat’s ear, identify the correct amount of ointment, and avoid contamination of the product. In addition, the vet can advise on monitoring for adverse reactions such as inflammation, excessive scratching, or changes in behavior, and outline steps to take if side effects appear.

Key discussion points with the veterinarian include:

Confirmation of ear mite presence through otoscopic examination or microscopic analysis.
Assessment of ear canal health and any underlying conditions.
Determination of the cat’s weight and age to calculate the exact dose.
Demonstration of the proper administration technique, including positioning, cleaning, and sealing the ear after application.
Recommendations for follow‑up appointments to evaluate treatment efficacy and decide on further interventions if needed.

Following the professional plan reduces the risk of ineffective treatment, resistance development, and unnecessary discomfort for the animal.

Gathering Necessary Supplies

Aversectin Ointment

Aversectin Ointment is a topical antiparasitic formulation designed for the treatment of ear mite infestations in felines. The product contains a concentration of active ingredients that eradicate Otodectes cynotis when applied directly to the ear canal.

Before use, verify the cat’s weight and health status; the recommended dose is 0.1 ml per kilogram of body weight, not exceeding the maximum volume specified on the label. Clean the external ear with a gentle, veterinarian‑approved solution to remove debris and wax, then dry the area with a soft cloth.

Application procedure:

Restrain the cat securely but gently to prevent injury.
Pull the auricle upward and backward to expose the ear canal.
Administer the measured amount of Aversectin Ointom into the canal, avoiding contact with the skin of the outer ear.
Keep the cat’s head tilted for 30 seconds to allow the ointment to coat the inner surfaces.
Repeat the process in the opposite ear, using the same dosage.

Post‑application monitoring includes checking for reduced scratching, decreased ear discharge, and absence of inflammation within 48 hours. If adverse reactions such as swelling, redness, or excessive discharge occur, discontinue treatment and consult a veterinarian promptly.

Store the ointment in a cool, dry place protected from direct sunlight. Keep the container tightly sealed and out of reach of children and other animals. The product remains effective until the expiration date printed on the packaging; do not use after this point.

Cotton Balls or Swabs

Cotton applicators are essential for delivering aversectin ointment into a cat’s ear canal without causing trauma. Choose sterile, high‑absorbency balls or individually wrapped swabs; avoid linty or scented varieties that may leave residues. Prior to use, wash hands, inspect the cotton for tears, and ensure the product is dry to prevent dilution of the medication.

When applying the ointment, follow these steps:

Gently restrain the cat, holding the head steady.
Pull the ear flap back to expose the canal.
Place a small amount of aversectin on the tip of the cotton ball or swab.
Insert the cotton just enough to reach the base of the canal; do not force it deeper.
Rotate the applicator lightly to spread the ointment across the inner walls.
Remove the cotton, allowing excess medication to drain naturally.
Reward the cat to reduce stress for future treatments.

Proper disposal of used cotton prevents cross‑contamination. Replace the applicator for each ear and each treatment session to maintain hygiene and effectiveness.

Gloves

Gloves are essential when administering aversectin ointment to a cat’s ears because they protect the caregiver from direct contact with the medication and any potential allergens. Selecting the appropriate glove type reduces the risk of contamination and ensures a clean application environment.

Use disposable nitrile gloves; they resist punctures and are chemically inert, preventing absorption of the ointment.
Choose a size that fits snugly to maintain tactile sensitivity while allowing full finger movement for precise placement of the cream.
Inspect each glove for tears or defects before use; replace any compromised pair immediately.
Wear gloves on both hands to avoid cross‑contamination between the cat’s ear and other surfaces.
After application, remove gloves by turning them inside out, seal them in a plastic bag, and discard in a waste container designated for medical waste.

Proper glove hygiene includes washing hands thoroughly before donning a fresh pair and after disposal. This routine minimizes the spread of mites and maintains a sterile field throughout the treatment process.

Treats for Your Cat

Aversectin ointment is a topical medication specifically formulated to eliminate ear mites in felines. Proper application maximizes efficacy and reduces the risk of irritation.

Before treatment, inspect the cat’s ears for debris, wax, or inflammation. Gently clean the outer ear canal with a soft cloth dampened with a veterinarian‑approved ear cleaner. Allow the ear to dry for a few minutes.

Apply the ointment as follows:

Dosage: Dispense the amount prescribed by the veterinarian, typically a small ribbon of ointment (approximately 0.5 cm) into the ear canal.
Position: Hold the cat’s head steady, tilt the ear upward, and gently pull the ear flap back to expose the canal.
Administration: Insert the tip of the tube into the canal without forcing it, then release the ointment slowly.
Massage: Rub the base of the ear for 10–15 seconds to distribute the medication evenly.
Repeat: Follow the dosing schedule indicated on the prescription, usually once daily for 3–5 days.

After each application, observe the cat for signs of discomfort, excessive scratching, or discharge. If adverse reactions occur, discontinue use and contact a veterinarian promptly.

Aversectin can be combined with other cat health products, such as flea preventatives and nutritional supplements, to support overall wellbeing. Ensure all treatments are compatible by consulting a veterinary professional before mixing medications.

Regular ear examinations, proper grooming, and adherence to the prescribed regimen are essential for preventing reinfestation and maintaining ear health in cats.

Step-by-Step Application Guide

Securing Your Cat

Applying aversectin ointment to treat ear mites requires that the cat be safely restrained to prevent injury to both the animal and the caregiver. Secure the animal on a stable surface, such as a table covered with a non‑slip mat, and use a towel or soft restraint bag to limit sudden movements without causing stress. A second person can hold the cat’s body while the primary handler focuses on the ear.

Key precautions:

Inspect the cat’s ears for excess wax or debris; clean gently with a veterinarian‑approved solution before treatment.
Position the cat’s head so the ear canal is accessible; tilt the head slightly upward to expose the opening.
Apply the prescribed amount of ointment using a sterile applicator, avoiding contact with the skin outside the ear canal.
Observe the cat for any immediate adverse reaction; if redness or swelling appears, discontinue use and contact a veterinarian.

After application, keep the cat in a quiet area for several minutes to allow the medication to settle. Avoid letting the cat scratch or shake its head vigorously; a short period of monitoring ensures the ointment remains in place and reduces the risk of secondary infection. Regular follow‑up appointments confirm the effectiveness of the treatment and verify that the cat remains secure during each administration.

Cleaning the Ear

Gentle Wiping

Gentle wiping prepares the ear canal for aversectin ointment and removes debris that can impede medication absorption. Use a soft, lint‑free cloth or gauze dampened with warm water. Squeeze excess liquid so the material is only slightly moist.

Hold the cat’s head securely but calmly; a second person may help restrain if needed.
Insert the dampened cloth just inside the outer ear opening—do not push deep into the canal.
Swipe outward in a smooth motion, covering the visible ear canal walls and the inner surface of the ear flap.
Discard the cloth after a single use to avoid re‑contamination.

After wiping, allow the ear to air‑dry for a few seconds before applying aversectin ointment. The cleaned surface improves drug contact and reduces the risk of irritation. If excess moisture remains, pat the area gently with a dry gauze piece before proceeding.

Removing Debris

Before applying aversectin ointment, clear all visible wax, crust, and dirt from the cat’s ear canal. Residual material blocks medication contact with mites and reduces absorption.

Gently lift the ear flap to expose the canal entrance.
Use a soft, lint‑free cloth or cotton ball dampened with warm water; avoid inserting anything deep into the ear.
Wipe outward, removing loose debris without pushing it further inward.
If thick wax is present, apply a few drops of a veterinary‑approved ear cleaner, let it sit for the recommended time, then repeat the wiping motion.
Dry the canal with a clean cotton pad before administering the ointment.

Complete removal of debris ensures the ointment reaches the affected area, maximizes therapeutic effect, and minimizes irritation.

Applying the Ointment

Correct Dosage

Accurate dosing of aversectin ointment is essential for effective elimination of ear mites in felines. The product is formulated for topical use; only the amount specified for the cat’s weight should be applied.

Cats up to 2 kg: 0.25 g (approximately a pea‑sized dab) per ear, once daily for three consecutive days.
Cats 2 kg–4 kg: 0.5 g per ear, once daily for three days.
Cats over 4 kg: 1 g per ear, once daily for three days.

Each dose must be measured with a sterile syringe or the supplied applicator to avoid excess. Apply the ointment directly into the ear canal, ensuring the tip reaches the base of the canal without forcing the material deeper than the tympanic membrane.

Adjustments are required if the cat exhibits severe infestation or if a veterinarian recommends a longer treatment course. In such cases, extend the regimen to five days, maintaining the same weight‑based dose. Do not exceed the maximum recommended amount; excessive application can cause irritation or systemic absorption.

Before each application, inspect the ear for debris or excess wax. Clean gently with a veterinarian‑approved solution, then dry the canal. Administer the calculated dose, massage the base of the ear for 30 seconds to distribute the ointment, and monitor the cat for adverse reactions such as swelling, redness, or discharge. If any signs appear, discontinue use and consult a veterinarian immediately.

Insertion Method

Applying aversectin ointment to a cat’s ear requires a controlled insertion technique to deliver the medication directly to the site of infestation. The procedure minimizes waste, reduces the risk of contamination, and ensures the active ingredient contacts the mites.

Begin by restraining the cat gently but firmly. Use a towel or a cat‑holding bag to limit movement without causing stress. Inspect the ear for excess wax or debris; remove visible buildup with a cotton ball moistened with a veterinarian‑approved ear cleaner. Allow the ear canal to dry for a few seconds before proceeding.

Insert the ointment using the following steps:

Squeeze a small amount of aversectin onto a sterile cotton swab or a disposable applicator tip; the dosage typically equals the length of the applicator tip.
Hold the cat’s ear flap upright with one hand to open the vertical canal.
With the other hand, gently introduce the applicator tip into the canal, advancing just far enough to reach the base without touching the tympanic membrane.
Release the ointment by applying gentle pressure to the applicator, allowing the medication to coat the inner walls of the canal.
Withdraw the applicator slowly, avoiding contact with the ear surface to prevent removal of the ointment.

After insertion, massage the base of the ear for 10–15 seconds to spread the ointment evenly. Observe the cat for any immediate adverse reactions such as excessive shaking, scratching, or signs of discomfort. Repeat the process in the opposite ear if both are affected, adhering to the prescribed treatment schedule.

Massaging the Ear

Massaging the ear helps distribute aversectin ointment evenly across the canal, ensuring contact with the mites and facilitating absorption. Begin by gently pulling the cat’s ear flap upward and backward to expose the ear canal. Apply a thin layer of ointment directly onto the skin inside the canal, avoiding excess that could drip out.

Use the pad of your thumb and index finger to massage the base of the ear in circular motions for 10–15 seconds. This motion pushes the medication toward the deeper sections where mites reside and breaks up debris that may block penetration. After massaging, release the ear flap and allow the cat to shake its head naturally; this action further spreads the ointment.

Key points to observe during the process:

Keep the cat calm; a soft voice and gentle handling reduce stress.
Do not insert fingers or tools deep into the canal; the massage should stay at the opening.
Perform the routine once daily, or as directed by a veterinarian, for the full treatment period.
Monitor the ear for signs of irritation; discontinue if redness or swelling increases and consult a professional.

Consistent ear massage combined with proper ointment application maximizes therapeutic effect and accelerates mite eradication.

Rewarding Your Cat

When treating feline ear mites with aversectin ointment, immediate positive reinforcement encourages cooperation and reduces stress. Offer the cat a preferred treat the moment the medication is applied, then repeat the reward after a short observation period to confirm the ointment remains in place.

Effective rewards include:

Small pieces of canned tuna or chicken, presented within a few seconds of application.
Commercial cat treats formulated for high palatability, limited to one or two pieces per session.
Brief petting or gentle chin scratches, timed to follow the treat.

Consistent use of these incentives creates an association between medication and a pleasant outcome, increasing the likelihood of a calm response during subsequent applications.

Post-Application Care and Monitoring

Observing for Side Effects

Allergic Reactions

Allergic reactions can occur when a cat receives a topical treatment for ear mites. The ointment contains active compounds that may trigger hypersensitivity in some animals, especially those with a history of skin or drug allergies.

Typical manifestations include:

Redness, swelling, or heat around the ear canal
Itching, scratching, or head shaking
Sudden discharge that is watery or contains blood
Facial edema or hives extending beyond the treated area

If any of these signs appear within minutes to hours after application, take the following measures:

Stop using the product immediately.
Gently rinse the ear with a veterinarian‑approved saline solution to remove residual medication.
Contact a veterinary professional for assessment; antihistamines or corticosteroids may be prescribed.
Observe the cat for systemic symptoms such as vomiting, lethargy, or difficulty breathing, and seek emergency care if they develop.

To reduce the likelihood of hypersensitivity, perform a small patch test on a discreet skin area before full application. Record the cat’s response for at least 24 hours. Use the recommended dosage strictly; excessive amounts increase exposure and risk. Maintain a log of all topical agents applied to the animal, enabling rapid identification of potential allergens in future treatments.

Irritation

Applying aversectin ointment to a cat’s ears can provoke irritation if the procedure is not performed correctly. Irritation may arise from three sources: the ear mite infestation itself, the chemical composition of the ointment, and mechanical trauma caused by improper application.

Infestation‑related irritation: Mites damage the ear canal lining, producing redness, swelling, and a gritty sensation. This baseline inflammation can amplify the cat’s discomfort during treatment.
Medication‑induced irritation: Aversectin contains active ingredients that may cause mild burning or itching, especially if the cat’s skin is already compromised. Observe for excessive redness, discharge, or increased scratching within 30 minutes of administration.
Application‑related irritation: Inserting a cotton swab too deeply or applying excessive pressure can damage the delicate ear canal. Use a soft applicator tip, spread a thin layer of ointment along the vertical canal wall, and avoid forcing the product into the deeper vestibule.

To minimize irritation, follow these steps:

Prepare the ear: Warm the ointment by holding the tube in the palm for a few seconds. Gently wipe excess debris with a damp, lint‑free cloth; do not insert cotton buds into the canal.
Administer the dose: Dispense the recommended amount onto the applicator tip. Place the tip at the entrance of the ear canal and allow the cat’s head to tilt naturally, letting the ointment flow inward by gravity.
Massage the base: Lightly massage the base of the ear for 10–15 seconds to distribute the ointment evenly. This action reduces localized buildup and eases discomfort.
Monitor the response: Check the ear after 15 minutes for signs of heightened irritation. If severe redness, swelling, or ulceration appears, discontinue use and consult a veterinarian promptly.

Consistent, gentle application reduces the risk of irritation while ensuring the ointment reaches the affected area, promoting effective mite eradication.

Follow-Up Treatments

After the initial application of aversectin ointment, continue treatment according to a strict schedule. Most veterinarians recommend a second dose 7 days after the first to eradicate any newly hatched mites. A third dose may be required 14 days later if symptoms persist.

Re‑examine the ears at each follow‑up appointment; look for reduced debris, less inflammation, and the absence of live mites.
Clean the ear canal gently with a veterinarian‑approved solution before each re‑application to remove excess wax and improve medication contact.
Record the cat’s behavior and any adverse reactions; report persistent itching, swelling, or discharge to the vet immediately.
Maintain a hygienic environment: wash bedding, vacuum carpets, and treat all animals in the household simultaneously to prevent reinfestation.
If the infestation does not resolve after the prescribed doses, the veterinarian may prescribe an oral acaricide or a different topical agent.

Adhering to the prescribed timeline and monitoring the cat’s response are essential for complete eradication and to avoid recurrence.

Preventing Reinfestation

Cleaning the Environment

Effective treatment of ear mite infestations in cats requires more than medication; the surrounding environment must be thoroughly cleaned to prevent re‑infestation. Residual eggs and larvae survive on bedding, furniture, and grooming tools, creating a continuous source of infection.

Remove all fabrics the cat contacts, such as blankets, pillowcases, and cushions. Wash at the highest temperature the material can tolerate, then dry on a hot setting.
Vacuum carpets, rugs, and upholstered furniture. Discard the vacuum bag or clean the canister immediately after use.
Clean hard surfaces with an EPA‑approved disinfectant. Pay special attention to corners, baseboards, and the areas around the cat’s feeding and sleeping stations.
Sanitize grooming accessories (brushes, combs) by soaking in a solution of diluted bleach (1 part bleach to 9 parts water) for five minutes, then rinsing thoroughly and air‑drying.
Replace any items that cannot be laundered or disinfected, such as worn‑out toys or damaged cushions.

After environmental decontamination, apply aversectin ointment directly into the cat’s ear canal according to the veterinarian’s dosage instructions. Repeat the application as prescribed, typically once daily for the recommended duration, while maintaining the cleaned environment throughout the treatment period. Continuous hygiene prevents the life cycle from completing, ensuring the infestation is fully eradicated.

Treating Other Pets

When ear mites are identified in a cat, other household animals should be examined and treated promptly to prevent reinfestation. Apply the same aversectin ointment to dogs, ferrets, or rabbits only after confirming species‑specific safety and dosage guidelines.

Verify that the animal’s species is listed as safe for aversectin use.
Clean the ear canal with a veterinarian‑approved solution; remove debris gently.
Apply the recommended amount of ointment directly into the ear canal; avoid excess that could cause irritation.
Massage the base of the ear for 30 seconds to distribute the medication.
Repeat the application according to the product’s schedule, typically once daily for three days.

Monitor each pet for signs of irritation, discharge, or persistent scratching. If adverse reactions occur, discontinue use and contact a veterinarian. Regular follow‑up examinations confirm eradication and reduce the risk of cross‑contamination within the household.

Important Precautions

Storage of Aversectin

Aversectin ointment must be kept in conditions that preserve its potency and prevent contamination. Store the product in its original container, tightly sealed, and protect it from light. The recommended temperature range is 2 °C to 8 °C (36 °F to 46 °F); do not freeze. If refrigeration is unavailable, a cool, dry place not exceeding 25 °C (77 °F) may be used for short periods, but efficacy may decline.

Key storage practices:

Keep the tube upright to avoid leakage.
Place the container away from direct sunlight and heat sources.
Do not expose the ointment to moisture; ensure the cap is securely closed after each use.
Record the expiration date; discard any product past this date or that shows discoloration, odor change, or separation.
Keep out of reach of children and pets to prevent accidental ingestion.

If a temperature excursion occurs (e.g., exposure to temperatures above 30 °C or freezing), replace the ointment before use on feline patients. Proper storage ensures consistent therapeutic effect when treating ear mite infestations in cats.

Handling Instructions

When treating feline ear mites with Aversectin ointment, follow these precise steps to ensure effectiveness and safety.

Verify the product’s expiration date and confirm the dosage recommended for the cat’s weight.
Wash hands thoroughly before handling the ointment.
Restrain the cat gently but securely; use a towel or a helper if necessary to prevent sudden movements.
Clean the ear canal with a veterinarian‑approved ear cleanser. Allow excess fluid to drain.
Apply a thin layer of the ointment directly into the ear canal, avoiding contact with the skin outside the canal. Use the tip of the applicator to reach the deepest part.
Massage the base of the ear for 10–15 seconds to distribute the medication evenly.
Repeat the procedure in the opposite ear if both are affected.
Observe the cat for any immediate adverse reaction such as excessive redness, swelling, or discharge. Contact a veterinarian if symptoms appear.

Additional handling guidelines:

Store the ointment in a cool, dry place away from direct sunlight.
Keep the container tightly closed when not in use to prevent contamination.
Do not use the product beyond the prescribed treatment period without veterinary guidance.
Dispose of any remaining ointment according to local regulations if it becomes contaminated or expired.

What to Do in Case of Overdose

If a cat receives more aversectin ointment than recommended, immediate action is essential to prevent systemic toxicity.

First, assess the situation. Determine the amount applied, the concentration of the product, and the time elapsed since administration. Record these details for veterinary consultation.

Second, contact a veterinarian without delay. Provide the cat’s weight, the estimated dose, and any observed signs such as vomiting, excessive drooling, lethargy, tremors, or respiratory distress. Follow the professional’s instructions precisely.

Third, if instructed, induce emesis within two hours of exposure, using a veterinarian‑approved emetic agent. Do not attempt to force vomiting if the cat shows signs of distress or if more than two hours have passed.

Fourth, administer activated charcoal if the veterinarian recommends it. The standard dose is 1–4 g/kg body weight, mixed with water to a paste consistency and given orally. Ensure the cat swallows the preparation; do not force it into the airway.

Fifth, monitor vital signs continuously. Check temperature, heart rate, and respiratory rate every 15–30 minutes. Note any changes and report them promptly.

Sixth, arrange for supportive care. Intravenous fluids may be required to maintain hydration and facilitate renal clearance. Anticonvulsants, anti‑emetics, or bronchodilators may be prescribed based on clinical signs.

Seventh, prevent recurrence. Store the ointment out of reach, use the exact dosage device supplied, and follow label instructions for each application.

Key steps in brief:

Assess dose and timing.
Call a veterinarian immediately.
Follow professional guidance on emesis and charcoal.
Monitor and record vital signs.
Provide supportive treatment as directed.
Implement safe storage and accurate dosing practices.

Prompt veterinary intervention and adherence to these measures reduce the risk of serious complications from an accidental overdose of ear‑mite ointment in cats.

When to Seek Veterinary Help Again

After the first dose of aversectin ointment, monitor the cat’s ears for persistent or worsening signs. Contact a veterinarian promptly if any of the following occur:

Redness, swelling, or heat that does not diminish within 48 hours.
Continuous discharge that is thick, foul‑smelling, or blood‑tinged.
Excessive scratching, head shaking, or signs of pain despite treatment.
Signs of systemic illness such as fever, lethargy, loss of appetite, or vomiting.
No improvement after the full course of medication, suggesting resistant mites or secondary infection.

Regular re‑examination is advisable two weeks after completing treatment to confirm eradication. If the cat’s condition deteriorates at any point, seek professional care without delay.