How should doxycycline 100 mg be taken after a tick bite?

How should doxycycline 100 mg be taken after a tick bite? - briefly

Take doxycycline 100 mg by mouth once daily, starting as soon as possible after the bite (ideally within 72 hours) and continue for 10–14 days. If gastrointestinal upset occurs, the dose may be taken with food to improve tolerance.

How should doxycycline 100 mg be taken after a tick bite? - in detail

After a tick exposure, a single daily dose of 100 mg doxycycline is recommended for prophylaxis. The medication should be taken orally with a full glass of water, preferably on an empty stomach; if gastrointestinal discomfort occurs, a light meal may be tolerated without compromising absorption. The course lasts for 21 days, beginning no later than 72 hours after the bite.

Key points for proper use:

  • Start the regimen within three days of the tick attachment.
  • Administer one tablet each morning to maintain consistent plasma levels.
  • Swallow the tablet whole; crushing or chewing reduces bioavailability.
  • Avoid antacids, calcium‑rich supplements, or iron products within two hours of dosing, as they bind doxycycline and diminish effectiveness.
  • For individuals with known hypersensitivity to tetracyclines, alternative prophylaxis must be considered.

Special considerations:

  • Pregnant or lactating persons should not receive doxycycline; alternative agents are required.
  • Children under eight years of age are excluded due to risk of tooth discoloration.
  • Renal or hepatic impairment may necessitate dose adjustment; consult a healthcare professional for guidance.

Potential adverse effects include mild nausea, photosensitivity, and esophageal irritation. To reduce esophageal discomfort, remain upright for at least 30 minutes after ingestion. If severe reactions such as persistent vomiting, rash, or signs of an allergic response develop, discontinue the medication and seek medical attention promptly.

Adherence to the full 21‑day schedule, even after symptom resolution, ensures optimal protection against Lyme disease and other tick‑borne infections. Monitoring for side effects and drug interactions throughout the treatment period supports safe and effective prophylaxis.