How many tick vaccinations are required?

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How many tick vaccinations are required? - briefly
A single dose of the tick vaccine is administered initially; a booster is recommended after 12 months to maintain protection.

How many tick vaccinations are required? - in detail
The number of immunizations needed to protect against tick‑borne diseases depends on the vaccine type, the species being vaccinated, and the vaccination protocol recommended by health authorities.
For dogs, the most common tick‑related vaccines target Lyme disease, Ehrlichiosis, and Anaplasmosis. The standard regimen consists of an initial series of two injections given three to four weeks apart, followed by an annual booster to maintain immunity. Some manufacturers also offer a three‑dose primary series, where the second dose is administered two weeks after the first and the third dose four weeks after the second; in this case, a single booster is given each year.
For cats, only the Lyme disease vaccine is widely available. The protocol mirrors the canine schedule: two doses spaced three to four weeks apart, then a yearly booster.
Human vaccination against tick‑borne illnesses is limited. Currently, a single dose of the Lyme disease vaccine (if approved in a given region) provides short‑term protection, with a recommended booster after one year. No routine series exists for other tick‑transmitted pathogens in humans.
Typical vaccination schedule

Canine Lyme, Ehrlichiosis, Anaplasmosis

First dose – any age > 8 weeks.
Second dose – 3–4 weeks later.
Annual booster – 12 months after the second dose.

Feline Lyme

First dose – any age > 8 weeks.
Second dose – 3–4 weeks later.
Annual booster – 12 months after the second dose.

Human Lyme (where available)

Single dose – adult or pediatric, per label.
Booster – 12 months after the initial dose.

Adjustments may be required for animals under six months, immunocompromised patients, or regions with high tick activity. Veterinarians and physicians should verify the specific product’s datasheet for exact timing and any additional doses.