How long is treatment for scabies mites?

How long is treatment for scabies mites? - briefly

A single dose of 5 % permethrin cream is applied for 8–12 hours and then washed off, with itching typically subsiding within a week. When oral ivermectin is prescribed, two doses spaced one week apart achieve cure in 7–10 days.

How long is treatment for scabies mites? - in detail

Treatment of scabies infestation typically follows a short‑term regimen, but the clinical resolution may extend beyond the medication schedule.

A single application of 5 % permethrin cream to the entire body, left on for 8–12 hours and then washed off, is the standard topical protocol. Because some mites survive the first dose, a second identical application is recommended 7 days later. This two‑dose schedule usually eliminates viable parasites within 48 hours after the first treatment, and the repeat dose addresses any newly hatched mites.

Oral ivermectin is an alternative for patients who cannot tolerate topical agents, have extensive disease, or require treatment of large groups. The usual regimen is a dose of 200 µg/kg taken on day 1, followed by an identical dose on day 7. In cases of severe crusted scabies, additional doses on days 14 and 21 may be prescribed.

Symptom relief does not occur immediately. Pruritus often persists for 2–4 weeks after the parasites are killed, reflecting the ongoing inflammatory response to dead mites and their debris. Antihistamines or topical corticosteroids may be used to control itching during this period.

Key timeline points:

  • Day 0: First topical or oral dose administered.
  • Day 1–2: Viable mites eradicated; no new burrows form.
  • Day 7: Second dose administered (topical re‑application or oral repeat).
  • Day 7–14: Majority of patients experience marked reduction in rash and itching.
  • Weeks 2–4: Residual itching may continue; symptomatic treatment recommended.

All household members and close contacts should receive the same therapeutic course simultaneously to prevent reinfestation. Bedding, clothing, and towels used within the preceding 72 hours must be washed in hot water (≥50 °C) and dried on high heat, or sealed in plastic bags for at least a week if laundering is not feasible.

In summary, the active pharmacologic phase lasts 1 week, with a repeat dose on day 7, while full clinical resolution may require up to one month of supportive care.