How long can a tick vaccine be stored? - briefly
The vaccine remains viable for up to 12 months when stored at 2 – 8 °C, and for up to 24 months if frozen at –20 °C. After these periods, potency cannot be guaranteed.
How long can a tick vaccine be stored? - in detail
The stability of a tick vaccine depends on temperature, container type, and formulation. Manufacturers typically assign a shelf‑life ranging from 12 to 24 months when the product remains unopened and stored at the recommended refrigeration temperature of 2 °C to 8 °C. Exposure to temperatures outside this range accelerates degradation of the active antigen and may render the vaccine ineffective.
Key factors influencing viable storage time:
- Refrigerated conditions: Continuous cooling within 2 °C–8 °C preserves potency; brief excursions above 10 °C should be avoided.
- Light protection: Opaque packaging prevents photolysis; storage in a dark environment is advised.
- Freeze‑avoidance: Freezing can damage adjuvant structures; ensure the product does not drop below 0 °C.
- Container integrity: Intact seals prevent contamination and moisture ingress; any breach shortens usable life.
Once the vial is opened, the remaining volume should be used within 28 days if kept under the same refrigerated conditions. Some vaccines include a preservative that extends this period; the specific duration is indicated on the product label. After reconstitution, the solution must be administered promptly; prolonged storage of the reconstituted product is not recommended.
Expiration dates printed on the packaging reflect the maximum time the vaccine retains its labeled potency when all storage guidelines are followed. Regular verification of temperature logs and visual inspection for discoloration or precipitation are essential quality checks before administration.