How can one contract tick‑borne encephalitis without a tick bite?

How can one contract tick‑borne encephalitis without a tick bite? - briefly

Infection can occur when virus‑containing tick saliva contacts a cut, abrasion or mucous membrane, or through ingestion of unpasteurised dairy products from infected livestock. Rarely, handling a tick without noticing its attachment may also transmit the virus.

How can one contract tick‑borne encephalitis without a tick bite? - in detail

Tick‑borne encephalitis virus (TBEV) can reach a human host without a visibly recognized tick attachment. Several pathways enable infection despite the absence of an obvious bite.

First, tick feeding may be imperceptible. Larval or nymphal stages are minute, often attaching for only a few hours before detaching. Their mouthparts can embed without causing pain or a noticeable lesion, allowing virus transmission during brief, unnoticed feeding periods.

Second, mucosal exposure to infected tick saliva is possible. Saliva expelled by a feeding tick can contact the eyes, mouth, or nasal passages if the host rubs the area or if the saliva aerosolises during removal attempts. The virus can cross mucous membranes and enter the bloodstream.

Third, contaminated surfaces present a risk. TBEV remains viable in tick excreta and in the environment for several days. Contact with contaminated soil, vegetation, or equipment followed by hand‑to‑mouth or hand‑to‑eye actions can introduce the virus.

Fourth, blood‑borne routes have been documented. Transmission can occur through transfusion of infected blood, organ transplantation, or needle‑stick injuries in laboratory or medical settings. The virus survives in stored blood products for limited periods, making these routes plausible.

Fifth, vertical transmission has been observed in animal models and rare human cases. Infected mothers may pass the virus to their offspring during pregnancy or delivery, bypassing the need for a tick bite.

Sixth, laboratory exposure remains a concern for researchers handling TBEV cultures. Accidental inhalation of aerosols or contact with contaminated gloves can result in infection.

Key points summarised:

  • Undetected tick feeding – larvae/nymphs, short attachment, no pain.
  • Mucosal contact – saliva reaching eyes, mouth, nose.
  • Environmental contaminationvirus persisting on surfaces, hand‑to‑mouth transfer.
  • Blood products – transfusion, organ graft, needle injury.
  • Maternal‑fetal transmissioninfection passed from mother to child.
  • Laboratory accidentsaerosol or dermal exposure during handling.

Understanding these mechanisms clarifies how TBEV infection can arise without a documented tick bite and underscores the need for preventive measures beyond simple bite avoidance.